Select The Perfect Nucleic Acid Delivery For Your Therapy
Successful delivery of nucleic acids requires the right combination of delivery tools and plasmids to ensure effective transfection and expression. Whether for research or therapeutic purposes, Sartorius nucleic acid and delivery solutions provide the flexibility, reliability, and efficiency required to support you from initial research to process development and commercial manufacturing.
- As every project stats with DNA. Discover our complete plasmid DNA offering with tailor-made plasmid engineering, manufacturing, off-the-shelf packaging plasmids for efficient and cost-effective scale up to commercial production
- Choose among our extensive portfolio of transfection reagents for viral vector and protein production and non-viral delivery solutions for in vivo and ex vivo nucleic acid delivery, such as lipid nanoparticles (LNPs). Our ready-to-use transfection reagents with pre-optimized protocol ensure high transfection efficiency while preserving cell viability and morphology
- Be ready to transition seamlessly from small- to large-scale manufacturing with flexible product volumes and quality grades available for research use to GMP grade
Nucleic Acid Solutions and Services
Progress with confidence in your research and ensure the level of performance you need, whether it be tissue-specific expression, high yield protein expression, RNA synthesis or high viral titers for therapeutic purposes.
We offer ready-to-use or tailor-made plasmids with fully flexible content designed by you and our plasmid scientists. Manufacture at any scale and at any quality grade from research to GMP grade.
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Transfection Solutions for R&D and Manufacturing
Sartorius transfection reagents are tailored for transient transfection, catering to a diverse array of applications such as viral vector manufacturing for cell and gene therapy (CGT), protein production, and life science research.
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Delivery Solutions for in vivo and ex vivo Therapies
Sartorius introduces a new selection of cationic lipids for LNP formulation and nucleic acid transfection reagents, suitable for both in vivo and ex vivo applications. Whether for research or therapeutic purposes, our products provide the flexibility, reliability, and efficiency required throughout your development journey.
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Explore Nucleic Acid Delivery Solutions
Featured Products
FectoVIR®-AAV
FectoVIR®-AAV transfection reagent guarantees higher rAAV titers, improves scalability for large scale production and de-risks manufacturing process with its availability at pharma GMP grade. FectoVIR®-AAV GMP is manufactured under a validated and aseptic process in compliance with ICH Q7, GMP part II guidelines, the quality grade of reference for active pharmaceutical ingredients (API).
Key Benefits:
- Process Economics: High AAV productivity expands the number of doses per batch to reduce manufacturing costs
- Industrial Scalability: Designed for large scale with low complexation volume, long complex stability, and high reproducibility
- GMP Grade Availability: Validated Manufacturing process following ICH Q7 guidelines, provided with full regulatory documentation
- Risks Mitigation: Both residual test and toxicity statement enable to mitigate risks and ensure patient safety
FectoVIR®-LV
FectoVIR®-LV is the next generation of transfection reagent, free of animal component, designed to improve LV productivity in HEK-293 cells and made for large scale manufacturing with reduction of the complexation volume and increased complex stability. FectoVIR®-LV benefits allow to increase number of doses produced per batch to treat more patient, while decreasing LV manufacturing costs.
Key Benefits:
- Productivity: Reach the highest Lentiviral vectors titers in HEK293 cells
- Cost-Effectiveness: Reduce your cost per batch with high titers and low DNA consumption
- Scalability: Produce at large scale with low complexation volume and long complex stability
- Time-Saving: Use DOE service to help you optimizing your process in a record time
in vivo-jetRNA®+
in vivo-jetRNA®+ is a non-viral delivery solution composed of pre-formed lipid-based nanoparticles. It has been specifically developed for in vivo mRNA delivery. Its high delivery efficiency combined with its safety make in vivo-jetRNA®+ an innovative alternative to lipid nanoparticles (LNPs), with the added advantage of being user-friendly with a two-step protocol
Key Benefits:
- Efficient: 100% mRNA encapsulation leading to delivery results comparable to LNPs while avoiding mRNA loss
- Time-Saving: Ready-to-use reagent that does not require formulation equipment or expertise
- Stable: Liposome transfection efficiency and size are stable over time
- Safe: Keep animals and organs healthy and do not trigger pro-inflammatory response
Custom Plasmid
Our online plasmid design platform offers a unique intuitive interface to modularly create any kind of plasmid, to fit your experimental needs. This online portal is also the entry-point to our plasmid manufacturing platform to produce plasmids, regardless of sequence complexity at Discovery grade, R&D, HQ and GMP grade.
Access our pDNA platform now
- Plasmid Engineering Service
- Whole Plasmid Sequencing Service
- Easy Plasmid Service
- Plasmid Manufacturing
